Three studies focus on genes responsible for autism
A large study of researchers on hundreds of families with autism found that natural mutations in the sperm and egg cells of parents will increase the risk of autism in the next generation, and the chance of fathers inheriting these mutations from the next generation is higher than that of their mothers. Four times.
These three new research findings were published in the journal Nature. The results show that mutations in some protein-coding genes called exomes play an important role in autism.
Such genetic mutations occur when the genetic codes cross, and most of them are harmless to the human body, but if they appear in the part of the genome required for brain development, they will cause serious problems. One of the three research teams found that these gene mutations may increase the risk of developing autism by 5-20 times.
Dr. Thomas Insel, director of the National Institute of Mental Health (NIMH) affiliated with the National Institutes of Health (NIH), said: "These findings confirm that it is not the size of the mutant gene but the mutant gene that increases the risk of disease (autism). s position."
The three research groups were led by Mark Daly of the Harvard and MIT Broad Institutes, Matthew State of Yale University, and Evan Eichler of the University of Washington. They identified hundreds of new possibilities that could eventually lead to development Suspicious genes for autism.
According to the latest data released by the US Centers for Disease Control and Prevention (CDC), there is an estimated autism in every 88 children in the United States. Scientists also believe that 80-90% of the causes of autism are genetically related, but most autism still cannot find the cause from known genetic causes.
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