Glass products are attractive in the field of pharmaceutical packaging materials

With the improvement of the pharmaceutical market in China and the classified management of prescription drugs and over-the-counter drugs, higher requirements are placed on pharmaceutical packaging. Today, domestic packaging companies are irrespective of their size, production technology, management level, product variety and quality. Significant progress has been made, new products and new technologies have been widely used, and backward products and technologies are gradually being eliminated.

The medicinal glass has already been widely used in the field of pharmaceutical packaging, and is still in the rising stage of development. Manufacturers should pay more attention to the upgrading of pharmaceutical glass itself, product upgrades, and integration with international standards.

Due to the effects of temperature, humidity, air, light, microorganisms, and insects, the stability of the drug may deteriorate. In this case, the advantages of the glass bottle are revealed because of its superior protection properties and good chemical stability. At the same time, the glass is not affected by the atmosphere and is not decomposed by solid or liquid substances of different chemical compositions. Characteristics, and by changing the chemical composition of the glass can adjust the chemical properties of glass and radiation resistance, therefore, glass has become the best drug, the most commonly used packaging containers. It also increases the market value and prospect of medicinal glass. In addition, according to the aesthetic principle and non-pollution principle of drug packaging material selection, medicinal glass is transparent and beautiful, and it is inexpensive and recyclable. Unlike post-processing of PVC materials, it is very difficult , brings extremely serious environmental problems.

Nowadays, due to its unparalleled characteristics and advantages, medical glass has been widely used in various packaging fields such as injections, powder injections, biological medicines, blood products, lyophilizers, tablets, and oral liquids in China. .

According to the different uses of products can be roughly divided into the following categories:

Pre-potting products: Injectors with pre-filled liquids are the most widely used. This product has the characteristics of no-clean, no-disinfection, and no-filling in clinical use. Greatly reduce the labor and cost spent from production to use. This technology and products have been used in foreign countries for many years.
The pre-filled injection container is mainly composed of three basic parts: injection syringe, push rod and rubber plug. The syringe can be glass or plastic and the injection dose is from 0.1 ml to 20 ml. Its production process is: cleaning and silicification of the syringe → thermal disinfection → into the sealed production line → assembly handles → filling injection → loading rubber plugs → loading needles → storage seal line → monitoring → loading push rods → labeling. All procedures that may affect the cleanliness of the drug solution are performed in a sealed clean room to ensure product safety and reliability.
The pre-filled injection container is actually a medicine package, which has the following advantages compared to the traditional packaging and injection methods:
1 High quality glass, plastic and rubber to ensure safety and reliability.
2 It saves the transfer of liquid medicine from the glass package to the syringe and reduces the waste caused by the adsorption of the drug.
3 Pre-filling is more accurate than manual infusion by medical staff.
4 Prevent cross-contamination in injections.
5 Name the drug on the injection container, it is not easy to make mistakes clinically.
6 It is easy to operate and saves 50% of time in clinical use than ampoules. It is especially suitable for emergency patients.
Infusion packaging: The domestic infusion packaging is mainly based on glass infusion bottles. Plastic infusion containers have gradually grown, but high-quality, lightweight Type II infusion bottles still have certain competitive advantages. The glass infusion bottle has the characteristics of smooth, transparent, easy to sterilize, erosion resistance, high temperature resistance, good sealing performance, and is still the preferred packaging for common infusion liquids.

Oral liquid packaging: Oral liquid preparations are mostly health products, most of which are packed in pharmaceutical glass, mainly controlled white and brown oral liquid bottles and molded brown glass medicine bottles.

Freeze-dried packaging: The lyophilized packaging contains the control bottles and molded bottles. Previously, there are ampoules and they are basically eliminated.

Tablets and Capsules Packaging: In recent years, tablets and capsules have been continuously replaced by plastic bottles, aluminum foils, etc. However, high-quality lightweight and light-resistant yellow or white glass bottles still have irreplaceable advantages and developments. space.
Powder injection packaging: powder injection is one of the five major pharmaceutical preparations in China, with various types of antibiotics as the main products, and its packaging is mainly molded injection bottle and controlled injection bottle. At present, in domestic powder injection packaging, molding injection bottles account for 70% to 80% and control injection bottles account for 20%-30%. The former is characterized by stable dimensions and high strength; the latter is characterized by light weight and good appearance transparency. At present, the controlled injection bottle has gradually increased at home and abroad.

Water injection packaging: The main form of water injection packaging is ampoule. There are two types of curved neck ampoules produced domestically: one is that there is a nick on the neck of the ampule, and there is a color point mark on the top of the nick; the other is that the neck of the ampule has a ring of low-melting glass color ring, because of the color ring and Ampoule glass itself has different coefficients of expansion, which can cause local stress and break easily.

China is currently in a period of rapid economic and technological development. Drug exports are increasing. Foreign businessmen are paying more and more attention to the quality of glass used in packaging medicines. Although in recent years, pharmaceutical glass production in China has made great progress, it is similar in the world. Compared with products, there is still a big gap in the production of pharmaceutical glass in China.